hrp0082p1-d2-79 | Diabetes (1) | ESPE2014

Sequence Analysis of 11 Known Causative Genes in Clinically Diagnosed Children as Maturity Onset Diabetes of Youth by Next Generation Sequencing

Agladioglu Sebahat Yilmaz , Aycan Zehra , Cetinkaya Semra , Bas Veysel Nijat , Onder Asan , Kendirci Havva Nur Peltek , Dogan Haldun , Ceylaner Serdar

Introduction: Maturity-onset diabetes of the youth (MODY), is a genetically and clinically heterogeneous group of diseases in the pancreatic β–cell that impair insulin secreation. It mostly caused by heterozygous mutations in one of 11 different genes associated with β–cell function. The aim of this study is detection of the distribution of both known and novel point mutations of these genes in Turkish population.Pati...